Snakes particularly the venomous types are important for pharmaceutical use. While the antihypertensive, angiotensin converting enzyme inhibitor (ACE inhibitor), had been isolated from the Jararaca (Bothrops jararaca), antidotes for snake bites are also being manufactured from other snake species. Venomous types have also been known for some anticoagulant properties. The following are five species of venomous snakes noted for their anticoagulant constituents.
Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics
Quinapril (Accupril) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. Quinapril is a prodrug. It is converted to its active metabolite, quinaprilat, in the liver.