When starting design, understanding grids and how to use them is a massive advantage. But once you've mastered them, you'll know how to break them. Don't be governed by the grid, govern the grid.
Design thinking is a proven and repeatable problem solving protocol that any business or profession can employ to achieve big results. Design thinking combines creative and critical thinking that allows information and ideas to be organised, decisions to be made, situations to be improved, and knowledge to be gained.