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(A) The epithelium of the small intestine consists of a series of crypts and villi. Stem and progenitor cells proliferate in the crypts, with their differentiated progeny moving upwards into the villi, where they are eventually shed into the intestinal lumen. (B) The stem cell niche is found at the base of the crypt. Stem cells express high levels of LGR5, and are found intercalated between Paneth cells, a specialized epithelial cell. (Credit: tthew F Pech and Steven E Artandi; EMBOJ) #NPG…

TRAPping telomerase within the intestinal stem cell niche

Age Related Dementia May Begin with Neurons’ Inability to Rid Themselves of Unwanted Proteins - Researchers discovered age related dementia likely results due to a declining ability of neurons to dispose of unwanted aggregated proteins. The image shows the chemical structure of neuroserpin, an accumulation of which was associated with age related dementia in mice within this study. More at NeuroscienceNews.com.

Researcher discover age related dementia likely occurs due to the declining ability for neurons to dispose of unwanted aggregated proteins.

A pie slice diagram shows the proportion of water to typical chemical components in a bacterial cell. Each chemical component is color-coded and is labeled by name and percent.

E-Book on cell biology

The evolution of the UPR shows conserved functions in immune responses.

The evolution of the UPR shows conserved functions in immune responses.

FREE Toxicology Course on Neurotoxicity, Anatomy and Physiology of the Nervous System, Cells of the Nervous System

FREE Toxicology Course on Neurotoxicity, Anatomy and Physiology of the Nervous System, Cells of the Nervous System Más

A historical timeline of selected advances leading to genome-scale engineering. (Credit: Kevin M Esvelt & Harris H Wang, MSB) Nature Publishing Group

A historical timeline of selected advances leading to genome-scale engineering. (Credit: Kevin M Esvelt & Harris H Wang, MSB) Nature Publishing Group

Insc mis-expression rotates the mitotic spindle, increases neuron numbers and generates ectopic cycling cells (credit: Raman M Das & Kate G Storey -EMBO reports) #vertebrate #neurogenesis; #asymmetric #cell fate; #mitotic spindle; #NPG

Insc mis-expression rotates the mitotic spindle, increases neuron numbers and generates ectopic cycling cells (credit: Raman M Das & Kate G Storey -EMBO reports) fate;

Therapeutic intervention in Wnt signalling. Components of Wnt signalling at the plasma membrane (PM), in the cytoplasm and nucleus are represented with the locus of intervention for some of the inhibitors (red text) described in this chapter. (Credit: Paul Polakis, EMBOJ) #NPG Nature Publishing Group

Drugging Wnt signalling in cancer

The extrinsic & intrinsic apoptosis pathways play a critical role in removing mutated or damaged cells.

The extrinsic & intrinsic apoptosis pathways play a critical role in removing mutated or damaged cells.

An overview of the flow of information from DNA to protein in a eukaryote (Nature Education)

Section 3 Extra Credit Resource: Gene expression

Infographic: Anatomy of a Cell - KIDS DISCOVER

Biology organelle Anatomy-of-a-Cell-Infographic-Kids-Discover

Immunofluorescence is a powerful technique that utilizes fluorescent-labeled antibodies to detect specific target antigens. This article presents key concepts in the use of antibodies in immunofluorescence and their application in the diagnosis of dermatologic diseases. (Credit: Ian Odell, JID) Nature Publishing Group

Immunofluorescence is a powerful technique that utilizes fluorescent-labeled antibodies to detect specific target antigens. This article presents key concepts in the use of antibodies in immunofluorescence and their application in the diagnosis of dermatologic diseases. (Credit: Ian Odell, JID) Nature Publishing Group

A stepwise epigenetic process controls immunoglobulin allelic exclusion  (Credit: Yehudit Bergman and Howard Cedar, Nat Rev Immunol) #NPG #sub

A stepwise epigenetic process controls immunoglobulin allelic exclusion (Credit: Yehudit Bergman and Howard Cedar, Nat Rev Immunol)

Metastatic cells can be present as dormant, quiescent solitary cells (Credit: Paul E. Goss & Ann F. Chambers, Nature Reviews Cancer) Nature Publishing Group

Metastatic cells can be present as dormant, quiescent solitary cells (Credit: Paul E. Goss & Ann F. Chambers, Nature Reviews Cancer) Nature Publishing Group

Disarming bacteria to beat infection

Disarming bacteria to beat infection

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