Explore Bile Production, To Look and more!

Explore related topics

Metastatic HCC. Key findings are the presence of many naked nuclei, as demonstrated here, as well as trabecular growth with disordered balls of cells. Other suggestive features to look for include branching fine capillary proliferation, endothelial cell wrapping around "packeting", macronucleoli, and evidence of bile production by malignant-appearing cells.

Metastatic HCC. Key findings are the presence of many naked nuclei, as demonstrated here, as well as trabecular growth with disordered balls of cells. Other suggestive features to look for include branching fine capillary proliferation, endothelial cell wrapping around "packeting", macronucleoli, and evidence of bile production by malignant-appearing cells.

Metastatic adenocarcinoma to brain

Metastatic adenocarcinoma to brain

Osteosarcoma. Had pleomorphic giant cells. The presence of spindle cells with delicate cytoplasm radiating from the nucleus suggests a sarcomatous process. This finding, in addition to the identification of pleomorphic and atypical giant cells, in the context of plasmacytoid polygonal cells, suggests osteosarcoma.

Osteosarcoma. Had pleomorphic giant cells. The presence of spindle cells with delicate cytoplasm radiating from the nucleus suggests a sarcomatous process. This finding, in addition to the identification of pleomorphic and atypical giant cells, in the context of plasmacytoid polygonal cells, suggests osteosarcoma.

The smears show cohesive groups of epithelioid cells that have abundant vacuolated cytoplasm, fairly distinct cell borders, moderate nuclear pleomorphism, round nuclei, and prominent nucleoli. The core biopsies show a neoplasm with delicate vasculature and epithelial cells with clear cytoplasm.

The smears show cohesive groups of epithelioid cells that have abundant vacuolated cytoplasm, fairly distinct cell borders, moderate nuclear pleomorphism, round nuclei, and prominent nucleoli. The core biopsies show a neoplasm with delicate vasculature and epithelial cells with clear cytoplasm.

Ewing/PNET. Calf of 11 year old boy.  Some of these cells form rosette-like structures. At high power, the lesion comprises of fairly monotonous, small round blue cells with scant cytoplasm, high N:C ratio, and multiple cytoplasmic vacuoles. The Papanicolaou-stained material demonstrates round to oval nuclei with multiple small nucleoli and occasional mitotic figures. Immunohistochemistry shows that the cells are immunoreactive for CD99

Ewing/PNET. Calf of 11 year old boy. Some of these cells form rosette-like structures. At high power, the lesion comprises of fairly monotonous, small round blue cells with scant cytoplasm, high N:C ratio, and multiple cytoplasmic vacuoles. The Papanicolaou-stained material demonstrates round to oval nuclei with multiple small nucleoli and occasional mitotic figures. Immunohistochemistry shows that the cells are immunoreactive for CD99

Wilms tumor, 2 yo boy. This case is an excellent example of Nephroblastoma (Wilms' tumor). Although the other tumors listed as answer choices are pediatric renal tumors only Wilms' tumor would show triphasic morphology. In addition to cytomorphologic differences there are useful discriminating clinical features of the pediatric renal tumors:  Nephroblastoma (Wilms' tumor):    Most common pediatric renal tumor.  Usual age at diagnosis is 2-5 yrs and is uncommon in infants less than 6 months…

Wilms tumor, 2 yo boy. This case is an excellent example of Nephroblastoma (Wilms' tumor). Although the other tumors listed as answer choices are pediatric renal tumors only Wilms' tumor would show triphasic morphology. In addition to cytomorphologic differences there are useful discriminating clinical features of the pediatric renal tumors: Nephroblastoma (Wilms' tumor): Most common pediatric renal tumor. Usual age at diagnosis is 2-5 yrs and is uncommon in infants less than 6 months…

melanoma The aspirates show markedly atypical cells in a single cell pattern. The cells are large with abundant cytoplasm and macronucleoli. Binucleated forms and cytoplasmic tails are also noted. Close inspection of the cytoplasm of some of the tumor cells reveals faint pigmentation (Image 4, center cell and lower right).

melanoma The aspirates show markedly atypical cells in a single cell pattern. The cells are large with abundant cytoplasm and macronucleoli. Binucleated forms and cytoplasmic tails are also noted. Close inspection of the cytoplasm of some of the tumor cells reveals faint pigmentation (Image 4, center cell and lower right).

Very cellular, but was just benign pancreas and pseudocyst

Very cellular, but was just benign pancreas and pseudocyst

Signed out as PTC with atypical features. Had a lot of matrix and lots of inclusions. The matrix material described above is the cytologic correlate with the abundant extracellular hyaline substance seen in histologic sections. The matrix could easily be confused with amyloid which raises the possibility of medullary thyroid carcinoma (MTC), which can have intranuclear pseudoinclusions. Clues in this case that PTC was not the diagnosis included the presence of the matrix material and the…

Signed out as PTC with atypical features. Had a lot of matrix and lots of inclusions. The matrix material described above is the cytologic correlate with the abundant extracellular hyaline substance seen in histologic sections. The matrix could easily be confused with amyloid which raises the possibility of medullary thyroid carcinoma (MTC), which can have intranuclear pseudoinclusions. Clues in this case that PTC was not the diagnosis included the presence of the matrix material and the…

Medullary thyroid cancer, amyloid.

Medullary thyroid cancer, amyloid.

Pinterest
Search