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Metastatic HCC. Key findings are the presence of many naked nuclei, as demonstrated here, as well as trabecular growth with disordered balls of cells. Other suggestive features to look for include branching fine capillary proliferation, endothelial cell wrapping around "packeting", macronucleoli, and evidence of bile production by malignant-appearing cells.

Metastatic HCC. Key findings are the presence of many naked nuclei, as demonstrated here, as well as trabecular growth with disordered balls of cells. Other suggestive features to look for include branching fine capillary proliferation, endothelial cell wrapping around "packeting", macronucleoli, and evidence of bile production by malignant-appearing cells.

Neurofibroma. The aspiration is very cellular and comprises of numerous cohesive spindle cell fragments and rare single cells (more apparent in the Papanicolaou stain). The nuclei in the smears are elongated and bland, while the core biopsy material shows associated small round inflammatory cells. Immunohistochemical stain on the core biopsy is strongly immunoreactive for S100 protein.

Neurofibroma. The aspiration is very cellular and comprises of numerous cohesive spindle cell fragments and rare single cells (more apparent in the Papanicolaou stain). The nuclei in the smears are elongated and bland, while the core biopsy material shows associated small round inflammatory cells. Immunohistochemical stain on the core biopsy is strongly immunoreactive for S100 protein.

Wilms tumor, 2 yo boy. This case is an excellent example of Nephroblastoma (Wilms' tumor). Although the other tumors listed as answer choices are pediatric renal tumors only Wilms' tumor would show triphasic morphology. In addition to cytomorphologic differences there are useful discriminating clinical features of the pediatric renal tumors:  Nephroblastoma (Wilms' tumor):    Most common pediatric renal tumor.  Usual age at diagnosis is 2-5 yrs and is uncommon in infants less than 6 months…

Wilms tumor, 2 yo boy. This case is an excellent example of Nephroblastoma (Wilms' tumor). Although the other tumors listed as answer choices are pediatric renal tumors only Wilms' tumor would show triphasic morphology. In addition to cytomorphologic differences there are useful discriminating clinical features of the pediatric renal tumors: Nephroblastoma (Wilms' tumor): Most common pediatric renal tumor. Usual age at diagnosis is 2-5 yrs and is uncommon in infants less than 6 months…

Osteosarcoma. Had pleomorphic giant cells. The presence of spindle cells with delicate cytoplasm radiating from the nucleus suggests a sarcomatous process. This finding, in addition to the identification of pleomorphic and atypical giant cells, in the context of plasmacytoid polygonal cells, suggests osteosarcoma.

Osteosarcoma. Had pleomorphic giant cells. The presence of spindle cells with delicate cytoplasm radiating from the nucleus suggests a sarcomatous process. This finding, in addition to the identification of pleomorphic and atypical giant cells, in the context of plasmacytoid polygonal cells, suggests osteosarcoma.

Very cellular, but was just benign pancreas and pseudocyst

Very cellular, but was just benign pancreas and pseudocyst

Lymfeklier metastase melanoom - PAP kleuring

Lymfeklier metastase melanoom - PAP kleuring

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