Non-invasive neuroimaging marker shows great potential for Alzheimer’s risk detection.
Individuals with amnestic mild cognitive impairment (aMCI) are at twice the risk of others in their age group of progressing to Alzheimer’s disease. Currently there is no conclusive test that exists to predict who will develop Alzheimer’s. Now, research from The University of Texas, University of Illinois, UT Southwestern and John Hopkins University is attempting to identify a potential biomarker that could offer a more complete picture of who is most at risk.
Researchers identify cellular regulator of glucose transport in the human body.
Researchers from UT Southwestern have gleaned a key cellular mechanism of how the body adjusts glucose levels, an important process that when abnormal can promote diabetes, cancer, and rare genetic diseases. The researchers determined that an enzyme called Protein Kinase C (PKC) can regulate whether more or less glucose should be transported into cells, serving as a kind of thermostat to ensure that proper levels are maintained.
Researchers identify new epigenetic pathway driving breast cancer progression.
Researchers at UT Southwestern Medical Center have uncovered how the body’s inflammatory response can alter how estrogen promotes the growth of breast cancer cells. The researchers have identified how a combination of signaling molecules inhibits the growth of breast cancer cells, improving clinical outcomes for some subtypes of breast cancers. The opensource study is published in Molecular Cell.
Researchers identify elusive cell type in the brain that control circadian rhythms.
A team of researchers form the UT Southwestern Medical Center and University of Tsukuba have identified key cells within the brain that are critical for determining circadian rhythms, the 24-hour processes that control sleep and wake cycles, as well as other important body functions such as hormone production, metabolism, and blood pressure. Circadian rhythms are generated by the suprachiasmatic nucleus (SCN) located within the hypothalamus of the brain, but researchers had previously been…