Columbia University Medical Center (CUMC) researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or eliminating the need for costly and potentially toxic immunosuppressant drugs and improving long-term transplant success. The study is published in Science Translational Medicine.
A 10th of children have a "monkey-like" immune system that stops them developing Aids, a study suggests. The study, in Science Translational Medicine, found the children's immune systems were "keeping calm", which prevented them being wiped out. An untreated HIV infection will kill 60% of children within two and a half years, but the equivalent infection in monkeys is not fatal.
Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males | Journal of Translational Medicine | Full Text
High-dose vitamin C injections shown to annihilate cancer - A team of researchers from the University of Kansas reportedly tested the effects of vitamin C given in high doses intravenously on a group of human subjects and found that it effectively eradicates cancer cells while leaving healthy cells intact.
Translational Medicine provides an immediate Open Access to its content making research freely available to the public which supports a greater global exchange of knowledge in the area of translational medicine.
An experimental treatment to stop the body attacking its own nervous system in patients with multiple sclerosis (MS) appears safe in trials. The sheath around nerves cells, made of myelin, is destroyed in MS, leaving the nerves struggling to pass on messages. A study on nine patients, reported in Science Translational Medicine, tried to train the immune system to cease its assault on myelin.
Intelligent bacteria, bactodetectors, have been programmed to successfully detect disease.
Another step forward has just been taken in the area of synthetic biology. Research teams from Inserm, CNRS (French National Centre for Scientific Research), Montpellier Regional University Hospital and Stanford University, have transformed bacteria into ‘secret agents’ that can give warning of a disease based solely on the presence of characteristic molecules in the urine or blood. To perform this feat, the researchers inserted the equivalent of a computer programme into the DNA of the…