#Schizophrenia: Ancient Scrolls, #Genomic Sequencing and Synaptic Pruning (NHGRI, March 18, 2016)
Synaptic Pruning Inside Neuron Synapse Geek Humor #learning #synapticpruning #inside #neuron #synapse #geek #humor #neurotransmitter #advice #learner #neuropsychology #wordsandunwords Here's a sticker featuring all key parts of a neuron / synapse along with the saying "Synaptic Pruning Inside".
For the first time, scientists have pinned down a molecular process in the brain that helps to trigger schizophrenia. The researchers involved in the landmark study, which was published Wednesday in the journal Nature, say the discovery of this new genetic pathway probably reveals what goes wrong neurologically in a young person diagnosed with the devastating disorder
Pruning starts near the time of birth & is completed at end of adolescents. At birth, the brain consists of ~86 billion neurons. The infant brain will grow 5x in size by adulthood. 2 factors contribute to this: the growth of synaptic connections between neurons, & the myelination of nerve fibers. A decrease in synapses is seen after adolescence (synaptic pruning), & ~50% do not survive until adulthood. Pruning is influenced by environmental factors and is widely thought to represent…
Network of nerve cells, including inset showing synapse between cells. Neuron, axons, dendrites, synapse and neurotransmitters are labeled. IMAGE CREDIT: Image courtesy of the National Institute on Aging.