RNA sequencing of 750-year-old barley virus sheds new light on the Crusades

RNA sequencing of 750-year-old barley virus sheds new light on the Crusades

PLNseq – a multivariate Poisson lognormal distribution for high-throughput matched RNA-sequencing read count data - High-throughput RNA-sequencing (RNA-seq) technology provides an attractive platform for gene expression analysis. In many experimental settings, RNA-seq read counts are measured from matched samples or taken from the same subject under multiple treatment conditions. The induced correlation therefore should be evaluated...

PLNseq – a multivariate Poisson lognormal distribution for high-throughput matched RNA-sequencing read count data - High-throughput RNA-sequencing (RNA-seq) technology provides an attractive platform for gene expression analysis. In many experimental settings, RNA-seq read counts are measured from matched samples or taken from the same subject under multiple treatment conditions. The induced correlation therefore should be evaluated...

CRISPR-CAS9 gene editing complex from Streptococcus pyogenes. The Cas9 nuclease protein uses a guide RNA sequence to cut DNA at a complementary site.

CRISPR-CAS9 gene editing complex from Streptococcus pyogenes. The Cas9 nuclease protein uses a guide RNA sequence to cut DNA at a complementary site.

RNA sequencing of 750-year-old barley virus sheds new light on the Crusades

RNA sequencing of 750-year-old barley virus sheds new light on the Crusades

RNA sequencing can potentially replace the current method to determine the mutation status of chronic lymphocytic leukemia cells - In a recent study, researchers from the Ohio State University demonstrated that complete IGH@ V-D-J sequences can be computed from unselected RNA-seq reads with results equal or superior to the clinical procedure: in the only discordant case, the clinical transcript was out-of-frame. Therefore, a single RNA-seq assay can simultaneously yield gene expression…

RNA sequencing can potentially replace the current method to determine the mutation status of chronic lymphocytic leukemia cells - In a recent study, researchers from the Ohio State University demonstrated that complete IGH@ V-D-J sequences can be computed from unselected RNA-seq reads with results equal or superior to the clinical procedure: in the only discordant case, the clinical transcript was out-of-frame. Therefore, a single RNA-seq assay can simultaneously yield gene expression…

CRISPR-CAS9 gene editing complex from Streptococcus pyogenes. The Cas9 nuclease protein uses a guide RNA sequence to cut DNA at a complementary site. Stylized image. RNA shaded red, DNA blue.

CRISPR-CAS9 gene editing complex from Streptococcus pyogenes. The Cas9 nuclease protein uses a guide RNA sequence to cut DNA at a complementary site. Stylized image. RNA shaded red, DNA blue.

RNA Sequencing Helps Unravel Disease Pathology In Atopic Dermatitis | MedicalResearch.com Medical Research Interviews and NewsMedicalResearch.com Medical Research Interviews and News

RNA Sequencing Helps Unravel Disease Pathology In Atopic Dermatitis | MedicalResearch.com Medical Research Interviews and NewsMedicalResearch.com Medical Research Interviews and News

Part 5 in this Genomic Series will examine the types of biological questions and problems RNA-Sequencing can address fully or be a key aid i...

Part 5 in this Genomic Series will examine the types of biological questions and problems RNA-Sequencing can address fully or be a key aid i...

New microRNA Analysis App in BaseSpace - miRNAs are a class of non-coding RNAs mainly involved in post-transcription control of gene expression although they are also involved in other non-canonical functions. Furthermore, they represents an interesting class of biomarkers for a large variety of diseases. Small RNA-sequencing is consolidating as the election method for the quantification of miRNAs. The steps needed to analyze Small RNA-sequencing data require the use of dedicated hardware…

New microRNA Analysis App in BaseSpace - miRNAs are a class of non-coding RNAs mainly involved in post-transcription control of gene expression although they are also involved in other non-canonical functions. Furthermore, they represents an interesting class of biomarkers for a large variety of diseases. Small RNA-sequencing is consolidating as the election method for the quantification of miRNAs. The steps needed to analyze Small RNA-sequencing data require the use of dedicated hardware…

Some RNA sequences have the ability to form a double helix, much like DNA. Scientists have recently successfully crystallized a short RNA sequence and used data  to confirm the hypothesis of a poly (rA) double-helix.

RNA double helix structure identified using synchrotron light

Some RNA sequences have the ability to form a double helix, much like DNA. Scientists have recently successfully crystallized a short RNA sequence and used data to confirm the hypothesis of a poly (rA) double-helix.

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