"I feel blessed to have worked with him and to have known him. He challenged me as an actress; he was always surprising and startlingly honest. He was an all too fleeting presence in my life, a beautiful young man who will always be in my heart." - Samantha Mathis
River Phoenix, 23 — Died Oct. 31, 1993: At only 23, Phoenix was already an award-winning actor when he died of a drug overdose at Johnny Depp's bar The Viper Room on Hollywood's Sunset Boulevard. The star of Running on Empty and My Own Private Idaho was at the bar with a small group, including girlfriend Samantha Mathis and younger brother Joaquin Phoenix, when River passed out at the bar.