The main difference is the whey protein isolate is processed further in the manufacturing of whey protein. The end result is a more pure protein, with much lower levels of lactose and fat. In fact, over 90% of whey protein isolate, by weight,is protein.
Optimum Nutrition Performance Whey Protein Powder, Whey Protein Concentrate, Whey Protein Isolate, Hydrolyzed Whey Protein Isolate, Flavor: Chocolate Shake, 50 Servings
Whey protein isolate is whey in it’s purest form. Whey protein isolate is the highest quality product and better than other whey protein as its contain 100% isolate protein inside. Compare to whey protein blend, hyrolyzed or concentrate, they have maybe around 50%-80% protein isolate inside which it is already blend with other non isolate source.