Discovery helps engineer more accurate Cas9s for CRISPR editing

Discovery helps engineer more accurate Cas9s for CRISPR editing

Discovery helps engineer more accurate for CRISPR editing - Scientists identified master controller of DNA cutting and have tweaked it to produce a hyper-accurate gene editor with the lowest level of off-target cutting to date.

by Tom Bunzel, Collective-Evolution Have you thought deeply about the latest discovery in genetics? DUF1220 – “DUF” stands for a (protein) domain of unknown function –presumably “junk DNA.” …

by Tom Bunzel, Collective-Evolution Have you thought deeply about the latest discovery in genetics? – “DUF” stands for a (protein) domain of unknown function –presumably “junk DNA.

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins.

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural domains. One domain may appear in a variety of different proteins.

Proteins are polymers of amino acids. The primary sequence of amino acids conveys to the protein the ability to fold into particular structures in three-dimensional space.  Thus a protein is a series of 3D domains strung together to give a protein a particular set of functions. For example, if death and EF hand domains are part of the same protein, the protein may trigger cell death with a rise in cellular calcium levels. New proteins are selected by evolutionary pressure when different…

Proteins are polymers of amino acids. The primary sequence of amino acids conveys to the protein the ability to fold into particular structures in thr

Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations

Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis.

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis.

The Human Brain with people

Protein Domain Found To Be Key At Explaining Evolution Of Human Brain Size

Junk DNA And Human Consciousness

Scientists have finally proven that our DNA has Telepathic abilities: Are we globally connected? Scientists refer to it as Genetic 'telepathy' and it is a

The search for the MS autoantigen - fools gold or a reality?  Sci Rep. 2016 Dec 23;6:39430. doi: 10.1038/srep39430. Antibodies from multiple sclerosis patients preferentially recognize hyperglucosylated adhesin of non-typeable Haemophilus influenzae.  Walvoort MT Testa C Eilam R Aharoni R Nuti F Rossi G Real-Fernandez F Lanzillo R Brescia Morra V Lolli F Rovero P Imperiali B Papini AM. Abstract In autoimmune diseases there have been proposals that exogenous "molecular triggers" i.e. specific…

The search for the MS autoantigen - fools gold or a reality?

Structure of ANOS1 gene and of anosmin-1 protein. Schematic representation of the ANOS1 gene location on the short arm of X chromosome, of anosmin-1 mRNA and protein structures and mutations. The number on the mRNA structure indicates the exons covering the ORF of the protein anosmin-1; shaded area indicates the exons involved in the coding of the different protein domains. The position of the CR domain, the WAP-like domain, the four FNIII repeats and the histidine-rich domain of anosmin-1…

a unified nomenclature for Kallmann syndrome 1 gene ( ) and

www.biology-direct.com - Figure 2

Bioinformatic flowchart and database to investigate the origins and diversity of Clan AA peptidases

Fusion protein of retinol‐binding protein and albumin domain III ...

Fusion protein of retinol‐binding protein and albumin domain III .

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme b... - PubMed - NCBI

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme b.

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