Superantigen - Wikipedia - Schematic representation of MHC class II.

Superantigen - Wikipedia - Schematic representation of MHC class II.

Difference between MHC Class I and MHC Class II proteins

Difference between MHC Class I and MHC Class II proteins

Mutant MHC class II epitopes drive therapeutic immune responses to cancer :  Nature :  Nature Publishing Group

Mutant MHC class II epitopes drive therapeutic immune responses to cancer : Nature : Nature Publishing Group

Antigenic peptides are processed within the cell and presented on the cell surface in association with class II MHC molecules. They then trigger the T-cell receptor on a T lymphocyte. Superantigens are not processed but bind to the class II MHC protein and to the V beta chain of the T cell receptor. A given superantigen activates a distinct class of T cells that express a certain V beta chain.

Antigenic peptides are processed within the cell and presented on the cell surface in association with class II MHC molecules. They then trigger the T-cell receptor on a T lymphocyte. Superantigens are not processed but bind to the class II MHC protein and to the V beta chain of the T cell receptor. A given superantigen activates a distinct class of T cells that express a certain V beta chain.

Stimulation of T-cell proliferation by conventional antigens (left) and bacterial superantigens (right). Both antigens are recognized only when presented to the T-cell antigen receptor (TCR) by a class II molecule of the major histocompatibility complex (MHC-II). Antigens are processed intracellularly by antigen-presenting cells (APC) and presented to the T cells as small peptides on a groove on the surface of MHC-II. In contrast, superantigens bind a different site on MHC-II, leaving the…

Stimulation of T-cell proliferation by conventional antigens (left) and bacterial superantigens (right). Both antigens are recognized only when presented to the T-cell antigen receptor (TCR) by a class II molecule of the major histocompatibility complex (MHC-II). Antigens are processed intracellularly by antigen-presenting cells (APC) and presented to the T cells as small peptides on a groove on the surface of MHC-II. In contrast, superantigens bind a different site on MHC-II, leaving the…

Pinterest • The world’s catalogue of ideas
Search