"The 25 Most Challenging Books You Will Ever Read" - I've read more than a few of these, but now that my pseudo-intellectual, post-grad literature days are over, I think that if your book can be described as "not reader friendly," you need to rethink what it means to be a writer. :)
Simple book cover, unadorned. Wordpress was named after a word from this book. Marshall McLuhan was inspired by James Joyce and specifically this book. Joseph Campbell used the term monomyth in The Hero with A Thousand Faces. Quarks were named after a phrase in this book. But it's probably unreadable and a waste of time.