Alexander the Great Miniature of Alexander the Great and his army make a sacrifice on the night before the Battle of Issus in Vasco da Lucena's French translation of Rufus's Historia Alexandri magni. Origin: Netherlands, S. (Bruges)
333 BC - Alexander the Great defeats Persia under Darius at battle of Issus. Alexander was the fourth in a line of great men and scholars: Socrates, Plato, Aristotle. Darius escapes and gathers his forces for the next battle.