Omega-3 Fatty Acids Inflammatory Diseases A PubMed study noted that EPA and DHA are anti-inflammatory and are beneficial in the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, lupus, multiple sclerosis, and migraine headaches. And that inflammation is also a strong factor in coronary heart disease, major depression, aging, and cancer.